Re: What PVE content can a couple of mates and I enjoy?

[Programmer]

Here you have (not completed list) https://forum.fonline-reloaded.net/index.php?topic=12879.msg105894#new

I can recommend:
- main quest
- caravan runs
- gun runners' mutants
- telltales
- dungeons from random encounters (Junktown's scouts)
- NCR Rangers quests
- jobs: bringing brahmin skins, armors, ropes for NPCs

[Programmer]

First: Complete this quest https://www.fonline-reloaded.net/wiki/index.php?title=A_Tent_in_the_Wasteland

Second: Start this quest https://www.fonline-reloaded.net/wiki/index.php?title=Blood-Soaked_Heroes (NPC will show when you complete first one).

For beginning: in short you must visit Vault 12 (Necropolis), Vault 15 and find quest related computers. Then you go to Vault City and visit Information Center (not Vault). Remember about reading full dialogs and console messages and also just in case save console messages because there isn't quest 's progress track.

Generally, for more good PvE content you have to find it on your own. Just play the game