Ok some of these can be used as quest or just a job.
I ll start will Junktown , here are few ideas.
1. I would use this one as quest.
Quest name : Easy Task
Quest giver : Andrew prison guard in Junktown.
Description(smth like this): When u talk to him , he ll seem disturbed , then you ll ask him is everything ok . He ll look suspicious and check you out and then say smth like can u help me for a moment i got an easy task for you. You ll accept or decline. He ll ask u if u can guard the jail for a few seconds , because he needs yo pee rly bad or to take a dump. Now here u can ask him is there anyone in jail , no one is coming for him or smth. He ll say its ok there no one in there just stay in fron of the jail till i come back. Of course he lied. And as u stand u are approached but few thugs that enter in dialog with u asking u to move and give them keys or die. U look confused , dont know whats happening and u have options to stand ground or escape as a baby.
2.Job
Job giver : Hernandez gambler in Junktown
He asks you for your help , to lend him some money , hes addicted to gamble he sure he found a way to win this time , because he discovered how system works. He promises that when he wins he ll give u bonus from your money. If u give him money , there some chance lets say 25% or 35% that he actually wins. Then u ll get double caps u invested and u ll get some exp. If he loses then nothing u lost your investment
3.Job
Job giver:Andrew prison guard in junktown.
The guy is fucking hungry he cant leave his post till his shift is over , and he got a criminal inside so he needs to be present every second and he asks you to bring him some food and water , but the thing is he only like food from NCR iguana sellers place , he usually buy enough food for months but it run over earlier than he hoped. And he needs water to you can fill up that thing u make from brahim skin.
4. Job
Job giver: Lars , head of guards in junktown.
The security at south gate is weak and they are having some problems in the evening with some thugs(raiders) what ever. He ask you if u can be stationed there at the door and help them out if something happens. Job is to stand at the gate for few hours in game time. There a chance for an encounter 30% or more , encounter would consist of some raiders or gun powder gang trying to get inside junktown. And you would help defending it. If there was no encounter then u finished your job by standing there exact time.
5. Quest
Quest name : Kidnapping
Quest giver : Lars , head of guards in junktown.
Description: One girl was kidnapped last night by some raiders while she was taking care of brahims in stables near junktown. They are low on guard so they cant go and check for trails atm . so they ask you to go and investigate. As u take quest u ll be shown new map location some small stables with brahims, theyre you ll see some blood and torn black jacket that raiders wear and small paper giving u the location of the raiders that took the girl. She seems to be able to make that paper in all the fuss. Paper will show u next location that u need to go , There you ll see guy with some guards , in dialog u learn that he actually buys people as slaves and then send me further where they ll work or be hookers or smth. U then torture him for informations , u learn who gave him the girl where they left , and also where he sent the girl. So you discover 2 locations you can go save the girl kill her captors and then go kill raiders that kidnapped her.
6.Job
Job giver : Marcelles = owns crash house.
Some punks are int he room , they are late with the rent , they are dirty and lound they dont want to leave the room , and the guards are too busy to do anything about it , they told he she needs to find a way to reason with them. So she ask you to actually reason with them and get them out. As you enter the room ( would make this different every time you do it) , first time u can find some junkies , next some , mercs , drunk soldiers... Anyway u can reason with them with speach , you can give them money to leave , or u can force them to leave them or u ll engage in combat and kill them or be killed
7.Quest
Quest giver : Marcelles
I would implement the same quest as in original fallout
http://fallout.wikia.com/wiki/Rescue_Sinthia tho change rewards alil bit . Its great quest and has good dialoge.
8. Quest
Quest name: Dangerous fugitive
Quest giver : Lars head guard or Mayor.
Description : Some dangerous guy that was in cell until ncr police come for him and take him to the ncr prison. He escaped in the meanwhile and he is dangerous , last time they captured him he took out few guards and because they are low on guards and its risky they cant spend any resources or people to find him and bring him to justice. So they ask you to bring him to justice , eventually kill him because he is too big of a problem. This guys is accused of rape , murder , robbery.They ll tell you information of his last out post where they caught him . You ll go there to check it for informations and trails. The place was swiped clean , theres nothing that can lead you to him. You go back to quest giver and inform him , he ll tell u that new informations came and that some worker saw him near quarry. You go to quarry talk with workers to see which one got the info about him. When u pay off one of them he ll tell you that he went to hide in the mountains and he ll give out the location. When you find him you ll see him with few guards. He ll offer you money to let him escape and some drugs( if he finds you strong) , you can let him escape for free because he told u sad story how he didnt do anything. Or you ll bring him to justice and kill him. If u are weak low lvl he ll auto att you when u enter his zone saying : Who the fuck are you? Get him boys , he ll make a fine slave.
If u like concept of these i can make more for other town.